Interpenetrating polymer network hydrogels with EGCG-MPN and nitric oxide for periodontitis

Key Points

• The research aims to evaluate the effectiveness of injectable hydrogels containing EGCG-MPN and nitric oxide for treating periodontitis.
• Developed interpenetrating polymer network hydrogels incorporating EGCG-MPN and nitric oxide.
• Conducted swelling ratio measurements to assess hydrogel behavior in periodontal pockets.
• Utilized in vitro assessments to evaluate biocompatibility and effectiveness against periodontitis-related bacteria.
• Hydrogels exhibited a reduced swelling ratio, minimizing excessive pressure in the periodontal pocket.
• Showed improved biocompatibility compared to traditional hydrogels.
• Demonstrated antibacterial activity against common periodontitis pathogens.