Why the study?
Does eptifibatide combined with accelerated alteplase, aspirin, and intravenous heparin improve the incidence and speed of reperfusion in patients with acute myocardial infarction?
Does eptifibatide combined with accelerated alteplase, aspirin, and intravenous heparin improve the incidence and speed of reperfusion in patients with acute myocardial infarction?
Combining eptifibatide with accelerated alteplase, aspirin, and intravenous heparin enhances the incidence and speed of reperfusion in acute myocardial infarction.
Should not alter AMI reperfusion practice; leaves open translation of enhanced experimental reperfusion to human outcomes.
The incidence and speed of reperfusion can be enhanced when a potent inhibitor of the glycoprotein IIb/IIIa integrin receptor, such as Integrilin, is combined with accelerated alteplase, aspirin, and intravenous heparin.
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Ohman et al. (1997) studied this question.
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