What question did this study set out to answer?

The study aims to assess thyroid function and serum amylase levels in patients with chronic kidney disease and their correlation with disease severity.

March 13, 2026CureusOpen Access

Thyroid Function Tests and Serum Amylase Levels in Chronic Kidney Disease: A Cross-Sectional Study Correlating Biochemical Changes With Disease Severity at a Tertiary Care Centre in India

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Authors

PSPranav SharmaJawaharlal Nehru Medical College ASAnil SamariaJawaharlal Nehru Medical College HTHarsh TakJawaharlal Nehru Medical College

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Implication

This cross-sectional study evaluates thyroid and amylase levels in chronic kidney disease, suggesting their importance in understanding disease severity.

Key Points

The study aims to assess thyroid function and serum amylase levels in patients with chronic kidney disease and their correlation with disease severity.
Conducted a cross-sectional observational study in a tertiary care centre in India.
Classified adult patients with chronic kidney disease into stages G1-G5 based on estimated glomerular filtration rate.
Measured thyroid function tests using chemiluminescent immunoassay.
Estimated serum amylase levels by enzymatic colorimetric methods.
Performed statistical analyses to compare biochemical parameters across CKD stages.
Significant differences were found in FT3 and FT4 levels across CKD stages (p=0.010 and p=0.003).
TSH levels exhibited a significant increasing trend across CKD stages (p=0.029).
Serum amylase levels increased in advanced CKD but did not show statistical significance (p=0.12).

Cite This Study

Sharma et al. (2026) studied this question.

synapsesocial.com/papers/69b3ab5e02a1e69014ccc2e4 https://doi.org/10.7759/cureus.104974

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Implication

This cross-sectional study evaluates thyroid and amylase levels in chronic kidney disease, suggesting their importance in understanding disease severity.

Thyroid Function Tests and Serum Amylase Levels in Chronic Kidney Disease: A Cross-Sectional Study Correlating Biochemical Changes With Disease Severity at a Tertiary Care Centre in India

Discussion

Member takes

Implication

Key Points

Cite This Study

Thyroid Function Tests and Serum Amylase Levels in Chronic Kidney Disease: A Cross-Sectional Study Correlating Biochemical Changes With Disease Severity at a Tertiary Care Centre in India

Discussion

Member takes

Implication

Key Points

Cite This Study

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