Distinct Prescription Patterns Emerge Years Before ALS Diagnosis: A Nationwide Registry‐Based Study

Key Points

• To investigate changes in prescription patterns leading up to ALS diagnosis over several years.
• Analyzed nationwide registry data
• Monitored prescription patterns over 6 years prior to ALS diagnosis
• Compared medication use trends in final year before diagnosis
• Prescription pattern changes were noted as early as 6 years before diagnosis.
• A significant increase in medication use was observed in the year leading to diagnosis.
• Findings support the existence of a prodromal phase before clinical ALS symptoms appear.