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March 1, 2026HLA

Fifteen Novel HLA Class I Alleles Identified in Haematopoietic Cell Transplant Recipients and Donors

Niamh McGregor M R Holloway A. J. French Thomas R. Turner Neema P. Mayor

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Key Points

The aim is to identify novel HLA Class I alleles in haematopoietic cell transplant recipients and donors.
Identification of HLA alleles in transplant recipients and their donors.
Analysis of genetic samples from both groups.
Use of advanced sequencing techniques to detect novel alleles.
Fifteen novel HLA Class I alleles were identified.
These alleles could improve compatibility in future transplants.
Findings indicate potential for better patient outcomes in HCT.

Implication

This research identifies novel HLA alleles in transplant recipients and donors, suggesting significant implications for transplant compatibility.

Abstract

Identification of 15 novel HLA alleles within haematopoietic cell transplant (HCT) recipients and donors.

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Cite This Study

McGregor et al. (2026) studied this question.

synapsesocial.com/papers/69b3ab9102a1e69014ccc82f https://doi.org/10.1111/tan.70635

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4Identification of 43 novel <scp>HLA</scp> alleles by <scp>PacBio</scp> single molecule real‐time sequencing in haematopoietic cell donors2024 · 4 citations
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