Cohort study assesses cervical cancer screening methods, finding limited benefits of cotesting and lower precancer risk with primary HPV testing.
In this cohort study of cervical cancer screen testing approaches and risk of cervical precancer, after a negative HPV test (regardless of cytology results) risk of precancer remained acceptably low throughout long-term follow-up. This suggests that cotesting yielded limited benefits, while increasing costs, relative to primary HPV testing.
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Gottschlich et al. (2026) studied this question.
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