Multimodal connectome analysis reveals cognitive dysfunction in unruptured brain arteriovenous malformations, indicating the need for improved risk strategies.
Cognitive dysfunction in bAVM represents a disconnection syndrome caused by the disruption of long-range white matter tracts rather than local cortical pathology. The dissociation between structural damage and functional compensation highlights the limitations of conventional volumetric assessment. Preoperative connectome mapping, particularly of white matter integrity, may improve risk stratification and functional preservation strategies.
No takes yet. Share an insight, caveat, or question.
Dong et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: