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Common and Distinct Features in Serum Proteomic Profiles in Keratoconus, Post-Laser Vision Correction Ectasia, and Pellucid Marginal Degeneration

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Uncovers shared proteomic features in ectasia conditions, suggesting common underlying mechanisms.

This research aims to identify shared and distinct serum proteomic profiles in keratoconus, post-laser vision correction ectasia, and pellucid marginal degeneration.
Analyzed serum proteomic profiles from individuals with keratoconus, post-laser vision correction ectasia, and pellucid marginal degeneration.
Examined the link between proteomic features and systemic inflammation.
Investigated the role of eye-rubbing behavior in the development of these conditions.
Identified common proteomic features across the ectasia conditions.
Observed links between systemic inflammation markers and proteomic profiles.
Suggests overlapping pathophysiological mechanisms for keratoconus and related conditions.

Jaskiewicz-Rajewicz et al. (2026) studied this question.

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