What question did this study set out to answer?

To assess the characteristics, treatment, and survival of chondrosarcoma patients using real-world data across Europe.

March 13, 2026Acta Oncologica0 citationsOpen Access

Characteristics, treatment and survival of patients with chondrosarcoma in five European countries: a DARWIN EU® cohort study

ABAnton BarchukErasmus MC CBCesar BarbozaErasmus MC JPJulieta PolitiErasmus MC

Key Points

To assess the characteristics, treatment, and survival of chondrosarcoma patients using real-world data across Europe.
Analyzed real-world data from chondrosarcoma patients in five European countries
Evaluated treatment approaches including surgery and systemic therapies
Assessed survival outcomes based on disease stage and grade
Most patients had early-stage, low-grade chondrosarcoma suitable for surgery
Survival rates were generally favorable, particularly for early-stage disease
Limited use of systemic therapies noted, especially in early disease stages

Abstract

This study demonstrates the feasibility of using real-world data across Europe to describe chondrosarcoma patients. Most had early-stage, low-grade disease amenable to surgery, with limited use of systemic therapies. Survival was generally favourable, except in advanced disease. Clinical trials remain difficult due to the rarity of advanced chondrosarcoma and the lack of standards.

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