Demonstrates enhanced cannabinoid efficacy in vitro with optimized serum conditions, suggesting improved cancer assessments.
The study demonstrates that serum concentration critically modulates the cytotoxic potency of cannabinoids. Reduced FCS enhances cannabinoid efficacy by limiting protein binding, emphasizing the need to optimize serum conditions for accurate in vitro cytotoxicity assessments.
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Mathibela et al. (2026) studied this question.
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