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March 13, 20260 citations

Enhancing the Diagnostic Performance of Early Lung Cancer by Integrating Multiplex Nucleic Acid Aptamer Detection With Conventional Tumor Markers: A Prospective Observational Study.

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HYHongxia YuanGansu Provincial Cancer Hospital Gansu Provincial Academic Instiute for Medical ResearchWWWeijun WangSun Yat-sen UniversityZWZhengli WeiSouth China Agricultural University

Key Points

  • The study aims to evaluate the effectiveness of combining nucleic acid aptamer detection with conventional tumor marker tests for diagnosing early lung cancer.
  • Conducted a prospective observational study
  • Integrated nucleic acid aptamer detection with conventional tumor markers
  • Evaluated diagnostic performance for early lung cancer
  • Enhanced diagnostic accuracy observed with the combined approach
  • Improved discriminative ability for early lung cancer detection
  • Indicative of a promising optimized strategy for early detection

Abstract

Integrating nucleic acid aptamer detection with conventional tumor marker testing enhances the diagnostic accuracy and discriminative ability for early lung cancer. The incremental value of this combined approach suggests a potential optimized strategy for early lung cancer detection.

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Cite This Study

Yuan et al. (2026) studied this question.

synapsesocial.com/papers/69b3acf302a1e69014ccf170https://doi.org/10.1097/coc.0000000000001316
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