Reveals that low factor XI activity correlates with advanced heart failure severity, suggesting its potential as a biomarker.
Reduced FXI activity is associated with adverse clinical and echocardiographic profiles in advanced HF. These findings support a potential biomarker or cardioprotective role for FXI and call for caution in applying FXI-targeted therapies in this population.
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Mansour et al. (2026) studied this question.
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