Clinicopathological and Molecular Characterization of Pediatric Breast Fibroepithelial Lesions: A Cohort Study.
Key Points
This research aims to characterize pediatric fibroepithelial lesions (FELs) at both molecular and clinical levels.
Conducted a cohort study of pediatric cases with breast fibroepithelial lesions.
Compared clinicopathological features of fibroadenomas and benign phyllodes tumors.
Analyzed the impact of lesion type on clinical outcomes.
No significant difference in clinical outcomes between fibroadenomas and benign phyllodes tumors.
Findings support the idea of a diagnostic continuum for pediatric FELs.
Prognostic significance of the distinction between FA and benign PT is limited.
Abstract
Pediatric FELs likely represent a diagnostic continuum. In this cohort, the distinction between FA and benign PT did not impact clinical outcome, suggesting limited prognostic significance.