What type of study is this?

This is a Human Clinical Trial study (also classified as: RCT).

What question did this study set out to answer?

To compare efficacy and safety of TAP block with ropivacaine combined with hydromorphone versus ropivacaine alone for analgesia.

March 14, 2026Journal of Pain Research0 citationsOpen Access

Comparing Ropivacaine with Hydromorphone in Ultrasound-Guided TAP Block for Cesarean Section

Effects of Transverse Abdominis Plane Block with Ropivacaine-Hydromorphone versus. Ropivacaine in Cesarean Section: A Randomized Controlled Trial

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Authors

JZJie Zhang DZDan Zhang YWYi Wang

Discussion

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Overview

Randomized trial shows enhanced postoperative analgesia and satisfaction in cesarean section with ropivacaine and hydromorphone, indicating improved management.

Key Points

To compare efficacy and safety of TAP block with ropivacaine combined with hydromorphone versus ropivacaine alone for analgesia.
Randomized controlled trial with 90 parturients scheduled for elective cesarean section.
Experimental group received TAPB with ropivacaine and hydromorphone; control group received ropivacaine alone.
Primary outcome measured was time to first rescue analgesia; secondary outcomes included PCA usage and satisfaction.
Time to first PCA use was longer in the experimental group (7.32 hours vs. 3.49 hours, p < 0.001).
Lower PCA consumption observed at 4, 12, 24, and 48 hours post-TAPB for the experimental group (p < 0.05).
Numerical rating scale scores were significantly lower in the experimental group at 4 and 12 hours (p < 0.05).
No significant differences in serum prolactin levels or adverse reactions between groups.

Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/69b4ad7918185d8a39800e26 https://doi.org/10.2147/jpr.s592353

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March 14, 2026Journal of Pain Research0 citationsOpen Access

Comparing Ropivacaine with Hydromorphone in Ultrasound-Guided TAP Block for Cesarean Section

Effects of Transverse Abdominis Plane Block with Ropivacaine-Hydromorphone versus. Ropivacaine in Cesarean Section: A Randomized Controlled Trial

View Full Paper

Ask AI

Bookmark

Authors

JZJie Zhang DZDan Zhang YWYi Wang

Discussion

Member takes

Overview

Randomized trial shows enhanced postoperative analgesia and satisfaction in cesarean section with ropivacaine and hydromorphone, indicating improved management.

Key Points

To compare efficacy and safety of TAP block with ropivacaine combined with hydromorphone versus ropivacaine alone for analgesia.
Randomized controlled trial with 90 parturients scheduled for elective cesarean section.
Experimental group received TAPB with ropivacaine and hydromorphone; control group received ropivacaine alone.
Primary outcome measured was time to first rescue analgesia; secondary outcomes included PCA usage and satisfaction.
Time to first PCA use was longer in the experimental group (7.32 hours vs. 3.49 hours, p < 0.001).
Lower PCA consumption observed at 4, 12, 24, and 48 hours post-TAPB for the experimental group (p < 0.05).
Numerical rating scale scores were significantly lower in the experimental group at 4 and 12 hours (p < 0.05).
No significant differences in serum prolactin levels or adverse reactions between groups.

Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/69b4ad7918185d8a39800e26 https://doi.org/10.2147/jpr.s592353

View Full Paper

Ask AI

Bookmark