Optimisation of through-vial Raman analysis of turbid samples by modelling the Raman intensity-depth decay response

Vasundhara Tyagi; Alex G Shard; Ryan T. Coones; Dimitrios Tsikritsis; Enya Murray; Elizabeth J. Legge; Caterina Minelli; Natalie A. Belsey

doi:10.1039/d6ay00130k

January 1, 2026Analytical MethodsOpen Access

Optimisation of through-vial Raman analysis of turbid samples by modelling the Raman intensity-depth decay response

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Key Points

This research aims to optimise through-vial Raman spectroscopy for turbid samples.
Modelling the Raman intensity-depth decay response
Assessing signal attenuation due to refraction, absorption, and scattering
Analysing the impact of turbid samples on spectral data
Demonstrated improvements in Raman signal quality
Reduced distortions and artefacts in spectral readings
Enhanced accuracy of chemical analysis in turbid settings

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Implication

Modelling reduces signal attenuation in turbid samples during non-destructive Raman analysis, suggesting improved chemical analysis.

Abstract

Raman spectroscopy enables non-destructive chemical analysis and can be performed through-vial, eliminating air exposure. However, signal attenuation arises from refraction, absorption, and scattering within the sample, while distortions and spectral...

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Cite This Study

Tyagi et al. (2026) studied this question.

synapsesocial.com/papers/69b4ad8d18185d8a39800f39 https://doi.org/10.1039/d6ay00130k

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Optimisation of through-vial Raman analysis of turbid samples by modelling the Raman intensity-depth decay response

Key Points

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Implication

Abstract

Discussion

Cite This Study

Optimisation of through-vial Raman analysis of turbid samples by modelling the Raman intensity-depth decay response

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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