TriNetX Real-World Data to Enhance Evidence-Based Respiratory Therapy Practice

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Key Points

To compare outcomes in COPD patients receiving versus not receiving pulmonary rehabilitation.
Queried TriNetX database for cohorts of COPD patients with and without PR participation.
Propensity matched cohorts for various demographic and clinical factors.
Compared hospitalizations, mortality, acidosis, and hypercapnia over a 3-year period.
Cohort 1 had a median of 2 hospitalizations; Cohort 2 had 7.
3-year survival probability was 82.1% for no PR and 73.4% for PR participants.
Cohort 1 had 3.5% hypercapnia and 3.3% acidosis; Cohort 2 had 28.9% hypercapnia and 22.6% acidosis.

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Analysis reveals reduced hospitalizations and mortality in COPD patients receiving respiratory therapy, indicating a need for greater PR utilization.

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Micheals et al. (2024) studied this question.

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