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Synapse
March 14, 20260 citationsOpen Access

How Can Explainable AI Improve Trust and Transparency in Medical Diagnosis Systems

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ANAinur NurzhanovaABAzhar BekbussinovaYBYerassyl Bolatkan

Key Points

  • This research examines how explainable AI impacts trust and adoption of AI in medical diagnostics.
  • Structured survey of 30 medical students
  • Expert interviews
  • Evaluation of AI decision confidence, perceived usefulness, and adoption intentions
  • Participants agreed AI explanations enhance clarity and safety of recommendations
  • Knowledge of XAI strongly correlates with trust (r = 0.48, p = 0.01)
  • Adoption intentions linked to perceived usefulness (r = 0.60, p = 0.001)

Abstract

The active adoption of AI in human services has provoked the problem of transparency and trust in decisions, since most healthcare AI systems are black-box models. To resolve these concerns, explainable Artificial Intelligence (XAI) has been suggested as a means of making medical AI tools safer, more reliable, and acceptable through human-readable explanations. This research paper describes the role of XAI in physician trust and acceptance of AI-based diagnostics. The knowledge of XAI, AI decision confidence, perceived usefulness, and adoption intentions were some of the main variables evaluated in a structured survey of 30 medical students and an expert interview. The findings indicate that participants unanimously concurred that AI explanations raise the clarity, safety and acceptability of AI recommendations. The knowledge of XAI showed a strong positive relationship with trust (r = 0.48, p = 0.01) and perceived usefulness (r= 0.60, p = 0.001). The model has demonstrated a steady reliability level (Cronbach a = 0.702) and accounted 48-52% variance. Although the study has some limitations, including the small size of the sample and self-reporting, it still has empirical evidence of the positive effect of XAI on human-AI collaboration on the necessary condition of successful integration of AI diagnostic tools in healthcare. Further studies need to be conducted in a clinical inquiry of XAI and determine institutional and patient attitudes.

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Cite This Study

Nurzhanova et al. (2026) studied this question.

synapsesocial.com/papers/69b4b9db18185d8a3980208ehttps://doi.org/10.5281/zenodo.18989435
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1How Can Explainable AI Improve Trust and Transparency in Medical Diagnosis Systems2026
  2. 2EXPLAINABLE ARTIFICIAL INTELLIGENCE IN HEALTHCARE: FROM ALGORITHMIC TRANSPARENCY TO TRUST AND SOCIAL ACCEPTANCE IN CLINICAL PRACTICE2026 · 1 citations
  3. 3Explainable AI (XAI) in healthcare: Enhancing trust and transparency in critical decision-making2024 · 66 citations
  4. 4Research and Analysis of Explainable Artificial Intelligence in the Medical Field2026
  5. 5Bridging the Gap Between Black Box AI and Clinical Practice: Advancing Explainable AI for Trust, Ethics, and Personalized Healthcare Diagnostics2024 · 12 citations