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Observational study links ocular surface inflammation and squamous metaplasia to dry eye symptoms in migraine patients, indicating potential pathogenesis involvement.
Objective signs and subjective symptoms of dry eye are common in patients with migraine. Abnormal CIC evaluation findings such as morphological changes in the bulbar conjunctiva, goblet cell loss, and squamous metaplasia suggest the presence of inflammation. These findings too, support the hypothesis that dry eye and changes in the ocular surface may play a role in the pathogenesis of migraine.
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Altaş et al. (2026) studied this question.
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