Transplantation of mitochondria enhances bioenergetics and neuroprotective effects in ischemic stroke, indicating potential for treating neurological disorders.
Astrocytic mitochondria transplantation is an effective therapeutic strategy for ischemic stroke. Its neuroprotective effects stem from the internalization of functional mitochondria into neurons and the subsequent flexibly regulation of endogenous mitochondrial dynamics, restoring bioenergetics and promoting neuronal survival. This approach holds significant promise for treating ischemic stroke and potentially other brain disorders involving mitochondrial dysfunction. ANN NEUROL 2026.
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Bian et al. (2026) studied this question.
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