Renal blood flow and progression to kidney failure in ADPKD

Kristen L. Nowak; Timothy P. Copeland; Elaine Ku; Mark J Sarnak; Zhiying You; Berenice Y. Gitomer; Kaleab Z. Abebe; Kyongtae T Bae; Arlene Chapman; Ronald D. Perrone; Frederic F. Rahbari-Oskoui; Vicente Torres; A. Ershova Yu.; Michel Chonchol

doi:10.1093/ndt/gfag059

March 11, 2026Nephrology Dialysis Transplantation

Renal blood flow and progression to kidney failure in ADPKD

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Key Points

This research aims to explore the relationship between renal blood flow and the progression to kidney failure in patients with ADPKD.
Assess baseline renal blood flow in early-stage ADPKD patients.
Analyze the association between renal blood flow and kidney failure progression.
Lower baseline renal blood flow correlates with a higher risk of kidney failure.
Findings suggest that monitoring renal blood flow may be crucial for early intervention.

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Implication

Findings show lower renal blood flow increases the risk of kidney failure in early-stage patients with ADPKD, indicating potential targets for monitoring.

Abstract

Lower baseline RBF independently associates with greater risk of progression to kidney failure in early-stage patients with ADPKD.

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Cite This Study

Nowak et al. (2026) studied this question.

synapsesocial.com/papers/69b4ba3618185d8a39802e9d https://doi.org/10.1093/ndt/gfag059

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Renal blood flow and progression to kidney failure in ADPKD

Key Points

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Implication

Abstract

Discussion

Cite This Study

Renal blood flow and progression to kidney failure in ADPKD

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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