Large PPM Lead–Associated Thrombus in a JAK2-Positive Patient

Key Points

• To examine the clinical significance of large intracardiac lead-associated thrombi in patients with JAK2 mutations.
• Case report of a JAK2-positive patient
• Assessment of thrombus size and characteristics with imaging
• Discussion on anticoagulation treatment options
• Evaluation of treatment decisions based on individual patient factors.
• Identification of a large intracardiac thrombus in a JAK2-positive individual
• Emphasis on the importance of individualized treatment plans for anticoagulation
• Discussion of clinical implications of lead-associated thrombi in patients with CIED.