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March 14, 2026JHLT OpenOpen Access

Five-Year Competing Risk Analysis of Infectious and Non-Infectious Complications After Lung Transplantation: Real-World Evidence from a Multicenter EHR-Based Cohort

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Authors

GCGerman ContrerasGGGeorge Golovko

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Overview

Analysis evaluates post-transplant outcomes in lung transplant recipients, highlighting infection and complication risks.

Key Points

  • The research aims to assess the 5-year incidence of complications in lung transplant recipients using a competing risks analysis.
  • Analyzed data from 10,648 lung transplant recipients
  • Utilized the TriNetX U.S. Collaborative Network
  • Employed the Aalen-Johansen method for cumulative incidence estimation
  • Identified major infectious and non-infectious complications
  • Conducted statistical analyses to determine outcome significance
  • Infectious complications had a 5-year cumulative incidence of 30.88%
  • Non-infectious complications had a 5-year cumulative incidence of 30.28%
  • Mortality rate was recorded at 10.62%
  • Cytomegalovirus (CMV) presented the highest infectious burden at 17.02%
  • Statistical analyses revealed significant differences across the identified outcomes (p < 0.001)

Cite This Study

Contreras et al. (2026) studied this question.

synapsesocial.com/papers/69b4fb1bb39f7826a300bba3https://doi.org/10.1016/j.jhlto.2026.100536
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