Nonequilibrium phases of a biomolecular condensate facilitated by enzyme activity

Sebastian Coupe; Nikta Fakhri

doi:10.1039/d5sm01106j

January 1, 2026Soft MatterOpen Access

Nonequilibrium phases of a biomolecular condensate facilitated by enzyme activity

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Key Points

To investigate how enzyme activity influences the regulation of biomolecular condensates in cells.
Examined the dynamics of biomolecular condensates under varying enzyme activities
Analyzed the structural configurations and interactions of condensates
Utilized experimental techniques to assess the impact of active processes
Identified distinct nonequilibrium phases of biomolecular condensates
Demonstrated that enzyme activity significantly alters condensate properties
Revealed a correlation between active regulation mechanisms and condensate stability

Implication

Explores mechanisms regulating biomolecular condensates in cells, highlighting the role of enzymes in organization.

Abstract

Biomolecular condensates represent a frontier in cellular organization, existing as dynamic macromolecular structures driven out of equilibrium by active cellular processes. Here we explore active mechanisms of condensate regulation by...

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Cite This Study

Coupe et al. (2026) studied this question.

synapsesocial.com/papers/69b4fbd5b39f7826a300c43f https://doi.org/10.1039/d5sm01106j

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Nonequilibrium phases of a biomolecular condensate facilitated by enzyme activity

Key Points

Implication

Abstract

Discussion

Cite This Study

Nonequilibrium phases of a biomolecular condensate facilitated by enzyme activity

Key Points

Implication

Abstract

Discussion

Cite This Study

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