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March 14, 2026Journal of obstetrics and gynaecology research0 citationsOpen Access

Fatal Intratumoral Hemorrhage in Mediastinal Diffuse Large B-Cell Lymphoma During Pregnancy

Fatal Intratumoral Hemorrhage in Mediastinal Diffuse Large B‐Cell Lymphoma During Pregnancy: A Case Report

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Authors

AYAtsuko YoshidaTKTakashi KajiTSTatsuro Sugimoto

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Overview

Case report uncovers fatal intratumoral hemorrhage in a pregnant woman with DLBCL, suggesting serious risks during treatment.

Key Points

  • To illustrate the complications and ethical issues associated with treating DLBCL in pregnancy.
  • Documented a case of a pregnant woman diagnosed with DLBCL at 16 weeks gestation.
  • Administered R-CHOP chemotherapy and initiated further treatment with DA-EPOCH-R.
  • Performed postmortem imaging to investigate the cause of sudden death.
  • Partial tumor shrinkage was achieved following chemotherapy.
  • The patient suffered a cardiopulmonary arrest due to massive hemoptysis.
  • Postmortem imaging revealed significant tumoral hemorrhage with bronchial communication.
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Cite This Study

Yoshida et al. (2026) studied this question.

synapsesocial.com/papers/69b4fc44b39f7826a300d10dhttps://doi.org/10.1111/jog.70232
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