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March 14, 2026Veterinary Record Case Reports

Urate urolithiasis in a 5‐week‐old Dalmatian with confirmed hereditary hyperuricosuria

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Authors

MDMartine DidierGMGiulia MangiagalliGRGinevra Riggio

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Overview

A case reports genetic confirmation of hereditary hyperuricosuria and its role in urate urolithiasis in a puppy, highlighting diagnostic importance.

Key Points

  • This case aims to highlight hereditary hyperuricosuria as a significant factor in urate urolithiasis.
  • Imaging to identify urinary bladder and urethral uroliths.
  • Genetic testing for the SLC2A9 mutation.
  • Conservative management with a low-purine diet and medical therapy.
  • Identification of multiple uroliths composed of ammonium urate.
  • Confirmation of homozygosity for the SLC2A9 mutation.
  • Importance of considering hereditary factors in very young dogs with urate urolithiasis.

Cite This Study

Didier et al. (2026) studied this question.

synapsesocial.com/papers/69b4fc7fb39f7826a300d6achttps://doi.org/10.1002/vrc2.70409
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