Retrospective study shows tailored therapy improves management of acute mediastinitis, highlighting the role of imaging and etiology.
The management of AM should be guided by initial disease severity. Surgical drainage is indispensable for severely ill patients with high qSOFA scores, while antimicrobial therapy alone is sufficient for stable patients with early-stage infections. Treatment should be individualized based on etiology, imaging, and clinical status.
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Zhang et al. (2026) studied this question.
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