Interactions Between Omega-3 Fatty Acids and Genetic Variants in Contributing to Cognitive Decline and Cardiovascular Disease Risk in Older Adults: A Systematic Review

Q: What type of study is this?

This is a Systematic Review study.

Fatima Al Qannas; Aoshuang Zhou; Danijela Gašević; John Ryan; Amy Owen

doi:10.1093/nutrit/nuag019

January 27, 2026Nutrition Reviews

Interactions Between Omega-3 Fatty Acids and Genetic Variants in Contributing to Cognitive Decline and Cardiovascular Disease Risk in Older Adults: A Systematic Review

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Key Points

To examine how omega-3 fatty acids interact with genetic variants in relation to cognitive decline and cardiovascular disease risk in older adults.
Conducted a systematic review of studies investigating omega-3 fatty acids and genetic variants.
Identified relevant literature from various databases regarding older adults.
Analyzed the interactions between dietary intake of omega-3 fatty acids and genetic predispositions.
Found that omega-3 fatty acids may have protective effects against cognitive decline.
Showed interactions between genetic variants and omega-3 intake influencing cardiovascular disease risk in older adults.
Research supports the potential role of diet in managing genetic risks during aging.

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Implication

Systematic review highlights that omega-3 fatty acids may influence genetic factors related to cognitive decline in older adults, suggesting potential risks for cardiovascular disease.

Abstract

PROSPERO registration No. CRD42024623183.

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Cite This Study

Qannas et al. (2026) studied this question.

synapsesocial.com/papers/69b6069b83145bc643d1c972 https://doi.org/10.1093/nutrit/nuag019

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Interactions Between Omega-3 Fatty Acids and Genetic Variants in Contributing to Cognitive Decline and Cardiovascular Disease Risk in Older Adults: A Systematic Review

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

Interactions Between Omega-3 Fatty Acids and Genetic Variants in Contributing to Cognitive Decline and Cardiovascular Disease Risk in Older Adults: A Systematic Review

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

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