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March 15, 2026Advanced Materials0 citations

Modular Assembly of Lipid Nanoparticles for Targeted mRNA Therapeutics and Vaccines (Adv. Mater. 15/2026)

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HXHu XuLanzhou City UniversityTLTianyao LiNational Center for Nanoscience and TechnologyQLQiyun LiShandong University

Key Points

  • This research aims to develop modular lipid nanoparticles for targeted mRNA therapeutics and vaccines.
  • Engineered modular lipid nanoparticles with protein and antibody linkers.
  • Surface-specific attachment of targeting ligands.
  • Customization for receptor-guided mRNA delivery.
  • Improved mRNA delivery effectiveness.
  • Enhanced customization in vaccine design.
  • Greater precision in targeting therapeutics.

Abstract

Lipid Nanoparticles This cover depicts a modular lipid nanoparticle engineered with plug-and-play protein and antibody linkers. By enabling rapid, surface-specific attachment of targeting ligands, the platform supports customizable and receptor-guided mRNA delivery, advancing precision therapeutics and vaccine design. More details can be found in the Research Article by Daming Wang, George F. Gao, Guangyu Zhao, Yuhong Cao, and co-workers (DOI: 10.1002/adma.202509199).

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Cite This Study

Xu et al. (2026) studied this question.

synapsesocial.com/papers/69b606d583145bc643d1d272https://doi.org/10.1002/adma.72617
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