Alcohol-induced oxidative stress triggers mitochondrial Ca²⁺ release through the permeability transition pore

Key Points

• The study aims to investigate how alcohol-induced oxidative stress affects mitochondrial calcium release.
• Utilized intravital liver imaging to observe cellular changes
• Employed fluorescence imaging techniques to track calcium dynamics
• Alcohol exposure led to significant mitochondrial calcium release
• Oxidative stress was linked to activation of the permeability transition pore