Efficacy of Sequential Transarterial Chemoembolization after Stereotactic Body Radiation Therapy versus Radiation Therapy Alone for Recurrent Hepatocellular Carcinoma: A Propensity Score-matched Analysis

Jian-Hui Wu; Junqiang Ding; Jing Sun; Wei-Ping He; Xuezhang Duan; Wengang Li

doi:10.14218/jcth.2025.00568

March 13, 2026Journal of Clinical and Translational HepatologyOpen Access

Efficacy of Sequential Transarterial Chemoembolization after Stereotactic Body Radiation Therapy versus Radiation Therapy Alone for Recurrent Hepatocellular Carcinoma: A Propensity Score-matched Analysis

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Key Points

This study evaluates the efficacy of sequential transarterial chemoembolization (TACE) after stereotactic body radiation therapy (SBRT) for treating recurrent hepatocellular carcinoma (HCC).
Conducted a comparative analysis of patients undergoing TACE after SBRT versus radiation therapy alone.
Utilized a propensity score-matched design to reduce bias in outcomes.
Focused on recurrent cases of hepatocellular carcinoma.
Found that combining TACE with SBRT led to improved treatment outcomes compared to radiation therapy alone.
Indicated potential enhancements in tumor response rates with the sequential approach.

Implication

Comparative analysis evaluates outcomes of TACE combined with SBRT in recurrent HCC, indicating potential benefits.

Abstract

Comparative data on sequential transarterial chemoembolization (TACE) after stereotactic body radiation therapy (SBRT) in recurrent hepatocellular carcinoma (HCC) remain limited. This study aimed to evaluate the efficacy of this combination.

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Cite This Study

Wu et al. (2026) studied this question.

synapsesocial.com/papers/69b64ccdb42794e3e660df81 https://doi.org/10.14218/jcth.2025.00568

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Efficacy of Sequential Transarterial Chemoembolization after Stereotactic Body Radiation Therapy versus Radiation Therapy Alone for Recurrent Hepatocellular Carcinoma: A Propensity Score-matched Analysis

Key Points

Implication

Abstract

Discussion

Cite This Study

Efficacy of Sequential Transarterial Chemoembolization after Stereotactic Body Radiation Therapy versus Radiation Therapy Alone for Recurrent Hepatocellular Carcinoma: A Propensity Score-matched Analysis

Key Points

Implication

Abstract

Discussion

Cite This Study

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