Analysis shows links between poststroke epilepsy and cognitive impairment in young stroke patients, suggesting complications.
We found independent associations between PSE and major VCD, and between PSE and cognitive impairment in the attention and working memory domain. This could support the "second-hit hypothesis," in which epilepsy following a primary injury relates directly to increased cognitive impairment with a subcortical neuropsychological profile.
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Reitsma et al. (2026) studied this question.
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