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Assessing the Role of Tandem Repeats in Shaping the Genomic Architecture of Great Apes | Synapse

November 4, 2011Open Access

Assessing the Role of Tandem Repeats in Shaping the Genomic Architecture of Great Apes

MFMarta FarréUniversity of Kent MBMontserrat BoschInserm FLFrancesc López‐GiráldezYale Cancer Center

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Resumen

Our observations provide evidence for the role of tandem repeats in shaping mammalian genome architecture. We hypothesize that an accumulation of specific tandem repeats in evolutionary regions can promote genome instability by altering the state of the chromatin conformation or by promoting the insertion of transposable elements.

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Cite This Study

Farré et al. (Fri,) studied this question.

synapsesocial.com/papers/69b87b588ad116708fe86866 https://doi.org/https://doi.org/10.1371/journal.pone.0027239

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