De novo assembly of the cattle reference genome with single-molecule sequencing

Benjamin D. Rosen; Derek M. Bickhart; Robert D. Schnabel; Sergey Koren; Christine G. Elsik; Elizabeth Tseng; Troy N. Rowan; Wai Yee Low; Aleksey V. Zimin; Christine Couldrey; Richard Hall; Wenli Li; Arang Rhie; Jay Ghurye; Stephanie McKay; Françoise Thibaud‐Nissen; Jinna Hoffman; Brenda M. Murdoch; W. M. Snelling; T. G. McDaneld; John A. Hammond; J.C. Schwartz; Wilson Nandolo; Darren E. Hagen; Christian Dreischer; Sebastian J. Schultheiß; Steven Schroeder; Adam M. Phillippy; John B. Cole; Curtis P. Van Tassell; George E. Liu; Timothy P. L. Smith; Juan F. Medrano

doi:10.1093/gigascience/giaa021

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Abstract

We demonstrate that improved continuity of assembled sequence warrants the adoption of ARS-UCD1.2 as the new cattle reference genome and that increased assembly accuracy will benefit future research on this species.

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Rosen et al. (2020) studied this question.

synapsesocial.com/papers/69b87b6ba1f51064fcd62c24 https://doi.org/10.1093/gigascience/giaa021

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De novo assembly of the cattle reference genome with single-molecule sequencing

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De novo assembly of the cattle reference genome with single-molecule sequencing

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