Descriptive analysis reveals epidemiological and susceptibility profiles in pneumococcal meningitis cases, suggesting treatment reconsideration.
Key Points
To describe the epidemiological profile of hospitalizations for pneumococcal meningitis and the susceptibility profile of S. pneumoniae in cerebrospinal fluid samples.
Descriptive retrospective analysis in a university hospital
Analysis of cerebrospinal fluid samples from hospitalized patients
Assessment of antimicrobial susceptibility
Identification of serotypes via laboratory testing
17 patients hospitalized with microbiologically confirmed pneumococcal meningitis
25% of pneumococcal isolates showed ceftriaxone resistance
Real-time PCR confirmed S. pneumoniae presence in 70% of samples
Case-fatality rate was 29.4%, with 12 of 17 patients discharged