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March 1, 2026HLA

Identification of the Novel HLA‐DRB1*07:174 Allele by Third‐Generation Sequencing

Romain Clément Laetitia Rivière Pauline Jamain I. Jollet

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Key Points

The aim is to identify and characterize the new HLA-DRB1*07:174 allele.
Utilized third-generation sequencing technology
Focused on specific nucleotide substitutions
Analyzed codon differences in exon 3
HLA-DRB1*07:174 identified as differing from HLA-DRB1*07:01:01:01
Difference due to a single nucleotide change in codon 112

Implication

Identifies the novel HLA-DRB1*07:174 allele through advanced sequencing, suggesting new genetic insights.

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Cite This Study

Clément et al. (2026) studied this question.

synapsesocial.com/papers/69b8f0f0deb47d591b8c5ac1 https://doi.org/10.1111/tan.70672

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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