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March 18, 2026BiomedicinesOpen Access

Turning Fluids into Data for Precision Oncology: A Multidisciplinary Tumor Board Approach to Malignant Pleural Effusions

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Authors

DDDomenico DamianiIGIlaria GirolamiEHEsther Hanspeter

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Overview

Narrative review integrates imaging and molecular profiling to enhance management of malignant pleural effusions in metastatic non-small cell lung cancer, suggesting improved outcomes.

Key Points

  • The primary objective is to synthesize contemporary knowledge on managing malignant pleural effusions, focusing on molecular testing's reliability and feasibility.
  • Conducted a narrative review of the management of malignant pleural effusions in metastatic NSCLC.
  • Integrated evidence from diagnostic imaging, procedural management, and molecular profiling.
  • Evaluated the diagnostic accuracy of cell-free DNA from pleural effusions.
  • Malignant pleural effusions present diagnostic and therapeutic challenges associated with poor prognosis.
  • Recent advancements show that pleural effusions can provide valuable prognostic information.
  • Liquid biopsy technology has become robust enough for routine use, enhancing patient management.

Cite This Study

Damiani et al. (2026) studied this question.

synapsesocial.com/papers/69ba432b4e9516ffd37a41d7https://doi.org/10.3390/biomedicines14030673
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