Compares polydipsia and polyuria in dogs, suggesting once-daily prednisolone may reduce water intake effectively.
Once-daily rather than divided-daily dosing is a reasonable option in dogs treated with oral prednisolone to reduce excessive water intake in the clinical setting. Urine specific gravity and osmolality can be used interchangeably for the assessment of urine concentration.
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Kouklaki et al. (2026) studied this question.
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