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March 18, 2026Lishizhen medicine and materia medica research0 citations

Research progress on the enhancement of endometrial receptivity in polycystic ovary syndrome by traditional Chinese medicine

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YLYawen LENGYWYu Xin WangXWXiaoke Wu

Key Points

  • This research aims to investigate how traditional Chinese medicine can enhance endometrial receptivity in patients with polycystic ovary syndrome (PCOS).
  • Systematic review of existing literature on traditional Chinese medicine effects on PCOS.
  • Analysis of mechanisms that improve blood supply and morphology of the endometrium.
  • Evaluation of the impact on immune microenvironment and potential reduction of ART-related damage.
  • Traditional Chinese medicine improves endometrial vascularization and function in PCOS patients.
  • It regulates various signaling pathways including PI3K/AKT and Wnt/β-catenin to enhance receptivity.
  • Findings suggest reduced hormonal and medication-related damage during ART procedures.

Abstract

多囊卵巢综合征(PCOS)是导致育龄期女性不孕的重要因素,当前治疗以促排卵和辅助生殖技术(ART)为核心。然而,PCOS患者因性激素失衡、糖脂代谢紊乱、子宫内膜局部炎症等因素导致的子宫内膜容受性障碍,仍是影响妊娠成功的关键难题。近年研究表明,中医药疗法可通过多途径提高PCOS子宫内膜容受性:通过改善子宫内膜血供、调节蜕膜化过程及肠道菌群组成,优化子宫内膜形态与功能;调控PI3K/AKT、TLR4/NF-κB/NLRP3、Wnt/β-catenin、MAPK/ERK等信号通路,促进子宫内膜血管生成并改善免疫微环境;同时减轻ART中激素及促排卵药物对子宫内膜的潜在损伤。文章系统综述了中医药改善PCOS子宫内膜容受性的研究及其作用机制,以期为提升PCOS患者生育能力提供新思路。

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Cite This Study

LENG et al. (2026) studied this question.

synapsesocial.com/papers/69ba43884e9516ffd37a4e9bhttps://doi.org/10.70976/j.1008-0805.szgygy-2026-0419
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