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Systematic review finds no support for BDNF as a diagnostic marker in pediatric bipolar disorder, suggesting further research is needed.
Current evidence does not support BDNF as a diagnostic biomarker for pediatric BD. Future studies with greater sample power and methodological standardization are needed to clarify its role in the risk and course of early-onset bipolar disorder.
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Ramos et al. (2026) studied this question.
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