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This research aims to assess the outcomes of unintentional single-substance exposures to factor Xa inhibitors in young children.

March 19, 2026Clinical Toxicology0 citations

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Acute unintentional single-substance pediatric exposures to direct factor Xa inhibitors reported to US Poison Centers, 2011–2019

MKMatthew KolbeckSUNY Upstate Medical University DRDeirdre K. ReganSUNY Upstate Medical University MHMichael HodgmanSUNY Upstate Medical University

Key Points

This research aims to assess the outcomes of unintentional single-substance exposures to factor Xa inhibitors in young children.
Analysis of data from US Poison Centers
Focus on children under 6 years of age
Evaluation of bleeding risks associated with exposures
Asymptomatic exposures are unlikely to lead to significant bleeding
No severe clinical outcomes reported in most cases
Findings suggest a low risk from unintentional exposure

Abstract

These data suggest that asymptomatic, unintentional, single substance exposures to factor Xa inhibitors in patients <6 years of age are unlikely to develop clinically significant bleeding.

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Acute unintentional single-substance pediatric exposures to direct factor Xa inhibitors reported to US Poison Centers, 2011–2019

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Abstract

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