Impact of timing, age and parity on clinicopathologic and prognostic factors in pregnancy-associated breast cancer

This study explores the pathological, clinical, and prognostic characteristics of pregnancy-associated breast cancer (PABC). Our findings challenge specific biological models by revealing no significant differences in local nodal involvement, lymphovascular invasion, pathological type, or hormone receptor status between the pregnancy and postpartum groups. Additionally, recurrence-free survival results revealed worse outcomes in the postpartum group compared to the pregnancy group; however, this disparity did not reach statistical significance. These results align with existing evidence but contradict findings from biological models.