What question did this study set out to answer?

The aim is to discuss the unique presentation of oncocytoma and retrorenal appendicitis in an HIV-positive patient.

March 19, 2026Clinical Case Reports0 citationsOpen Access

Renal Oncocytoma With Retrorenal Appendicitis: An Uncommon Juxtaposition of Neoplastic and Inflammatory Processes in the Context of HIV Infection

MSMohammed Salah E. Khalifa SalemUniversity of the Witwatersrand NPNathan PoppletonUniversity of the Witwatersrand JVJacob VargheseKennedy Krieger Institute

Key Points

The aim is to discuss the unique presentation of oncocytoma and retrorenal appendicitis in an HIV-positive patient.
CT scan imaging to identify dual pathology
Multidisciplinary planning for surgical intervention
Pathological evaluation and immunohistochemistry for diagnosis
CT scan showed a large renal mass indicating oncocytoma
Retrorenal appendicitis was also detected in the same patient
Same-sitting surgery was justified based on the team's assessment

Abstract

ABSTRACT In HIV‐positive patients, a blunted inflammatory response can mask retrorenal appendicitis, leading to atypical flank or abdominal pain. We report a case of dual pathology on CT scan involving retrorenal appendicitis and a large renal mass with a central scar suggesting oncocytoma. This highlights how multidisciplinary team planning can justify same‐sitting surgery, while pathology and immunohistochemistry secure the final diagnosis and guide follow‐up.

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