Fetoscopic laser management of triplet pregnancies complicated by twin-twin transfusion syndrome

Evangelia Vlachodimitropoulou; Sidika Naz Dagli; Grace Ng Yang Huang; Tim Van Mieghem; Johannes Keunen; Nimrah Abbasi; H Flores-Mendoza; Greg Ryan

doi:10.1159/000551563

March 17, 2026Fetal Diagnosis and Therapy

Fetoscopic laser management of triplet pregnancies complicated by twin-twin transfusion syndrome

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Key Points

This research aims to evaluate the perinatal outcomes of triplet pregnancies affected by twin-twin transfusion syndrome treated with fetoscopic laser ablation compared to twin pregnancies.
Retrospective review of 42 triplet pregnancies complicated by TTTS treated with FLA.
Comparison with outcomes from 1072 MC/DA twin pregnancies treated with FLA.
Statistical analyses performed using Chi-square/Fisher’s exact test and Mann-Whitney U test.
No significant difference in Quintero stage distribution between triplets and twins.
Survival of unaffected triplet was 88.1%; dual neonatal survival in TTTS-affected pairs was 61.9%.
Survival outcomes for triplets were similar to MC/DA twins, with dual survival at 70.1%.

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Implication

Evaluates outcomes of triplet pregnancies with twin-twin transfusion syndrome treated with fetoscopic laser ablation, indicating similar results to twin pregnancies.

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Cite This Study

Vlachodimitropoulou et al. (2026) studied this question.

synapsesocial.com/papers/69bb929b496e729e629801a6 https://doi.org/10.1159/000551563

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Fetoscopic laser management of triplet pregnancies complicated by twin-twin transfusion syndrome

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Fetoscopic laser management of triplet pregnancies complicated by twin-twin transfusion syndrome

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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