Results of red cell antibody screening assays from 2,500 laboratories in 10 external quality assessment programs: sensitivity for anti-D.

Christoph Buchta; Willy A. Flegel; Wim Coucke; Cécile Toly-Ndour; Agnès Mailloux; Karina Hellbert; Gianfranco Avveduto; Isabelle Bertin-Jung; Anna Bode; Lobna Bouacida; Stefanie Gemein; Sabine Goseberg; Andrea Griesmacher; Richard Haggas; Junho Kim; Truscha Niekerk; Jean-Pascal Siest; Nanna Skeie; Heidi Støen; Renate Becker; TOF Wagner; Günther F. Körmöczi

doi:10.2450/bloodtransfus.1277

Key Points

The study aims to evaluate the effectiveness of red cell antibody screening assays in various laboratories and suggest improvements.
Assessed antibody screening assays from 2,500 laboratories across 10 external quality assessment programs.
Evaluated sensitivity for anti-D antibodies in the screening tests.
Analyzed the results to identify options for enhancing antibody detection.
Found varying sensitivity levels for anti-D antibodies across different laboratories.
Identified key areas for practice changes to optimize routine strategies in antibody screening.
Provided guidance for further studies on the clinical impact of improved detection methods.

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Implication

Quality assessment programs improve antibody detection in laboratories, suggesting changes in routine practices.

Abstract

The results show options for action to improve antibody detection, may support a practice change to optimize routine strategies of red cell antibody screening, and can guide studies to evaluate the clinical impact.

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Cite This Study

Buchta et al. (2026) studied this question.

synapsesocial.com/papers/69bb92d1496e729e6298077e https://doi.org/10.2450/bloodtransfus.1277

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Results of red cell antibody screening assays from 2,500 laboratories in 10 external quality assessment programs: sensitivity for anti-D.

Key Points

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Implication

Abstract

Discussion

Cite This Study

Results of red cell antibody screening assays from 2,500 laboratories in 10 external quality assessment programs: sensitivity for anti-D.

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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