Research reveals how cell-cell adhesion influences behavior in cellular communities, highlighting important interactions.
The cell biology of tissues challenges us to understand how fundamental processes found in free living as well as communal cells are coordinated to achieve complex patterns of behavior on the scale of cellular populations. In this issue, Soffer et al. (https://doi.org/10.1083/jcb.202502071) reveal how cell–cell adhesion co-opts the spectrin membrane skeleton to achieve this goal in the epidermis of the skin.
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Lwin et al. (2026) studied this question.
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