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March 19, 2026Angewandte Chemie International Edition7 citationsOpen Access

Near‐Infrared‐Light‐Driven Photochemistry and Photocatalysis: Mechanisms, Recent Applications, and Opportunities in Organic Synthesis and Biology

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SPSantosh K. PagireWOWesley J. OlivierDMDebabrata Maiti

Key Points

  • The aim is to explore the mechanisms and applications of near-infrared (NIR) photochemistry and photocatalysis in synthetic and biological contexts.
  • Focused on recent contributions and developments since 2019
  • Discussed properties of NIR methods including penetration depth and safety
  • Integrated perspectives from organic synthesis and biology
  • Demonstrated advantages of NIR methods over traditional light methods
  • Highlighted the potential for scalability in reactions
  • Showed applicability in complex biological environments

Abstract

ABSTRACT Near‐infrared (NIR) photochemistry and photocatalysis have emerged as powerful extensions of analogous visible‐light methods, offering unique advantages, such as deeper penetration through opaque media, minimal background absorption, reduced scattering, more selective photon absorption, and enhanced safety profiles. These properties enable reactivity in complex environments, are more amenable to scale‐up in batch processes, and permit reactions in biological settings that remain challenging for traditional ultraviolet and visible‐light manifolds. This minireview focuses exclusively on the true NIR regime (700–1000 nm) and integrates both synthetic and biological perspectives, which establish this area as a rapidly expanding frontier with broad opportunities. Emphasis is placed on contributions reported since 2019.

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Cite This Study

Pagire et al. (2026) studied this question.

synapsesocial.com/papers/69bb9357496e729e6298172bhttps://doi.org/10.1002/anie.202526147
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