Targeting Yy1, Bmp7, and Ctgf pathways represents a potential novel therapeutic strategy for LMNA-related dilated cardiomyopathy.
Our findings demonstrate that upregulation of Yy1 or co-modulation of Bmp7 and Ctgf offer novel therapeutic strategies for the treatment of DCM caused by LMNA insufficiency.
Tan et al. (Mon,) studied this question.
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