Observational study links sleep disruption with long-term cognitive impairment in ICU survivors, suggesting a glymphatic pathway.
Sleep disruption is nearly universal during critical illness and is increasingly linked to long-term cognitive impairment among intensive care unit survivors. Advances in neuroscience have highlighted the glymphatic system – a brain-wide perivascular network that clears metabolic waste such as β-amyloid and phosphorylated tau – as a plausible mechanism connecting sleep disturbance to adverse neurocognitive […]
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Alshammari et al. (2026) studied this question.
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