Detectable ctDNA predicts recurrence and disease upstaging in high-risk non-muscle invasive bladder cancer, indicating worse outcomes.
Detectable ctDNA status for high-risk NMIBC pre-RC was associated with worse RFS, increased risk of pathological upstaging, and locally advanced disease with lymph node metastasis.
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BEN-DAVID et al. (2026) studied this question.
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