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March 10, 2026The Turkish Journal of GastroenterologyOpen Access

Association of Early Heparin Use with Mortality in Cirrhotic Patients: A Retrospective Cohort Study

Maodong Guo Tao Ling Jie Ding Xin Shi

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Key Points

To investigate the relationship between early heparin use and mortality rates in cirrhotic patients.
Conducted a retrospective cohort analysis
Included cirrhotic patients who received heparin early in treatment
Evaluated 30-day mortality and RBC transfusion rates
Early heparin use was associated with lower 30-day mortality rates
No significant increase in RBC transfusion risk was observed

Implication

Retrospective cohort study finds early heparin use reduces mortality in cirrhotic patients, suggesting potential benefits.

Abstract

Early heparin use was associated with reduced 30-day mortality among cirrhotic patients, without increasing the risk of RBC transfusion.

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Cite This Study

Guo et al. (2026) studied this question.

synapsesocial.com/papers/69be34f26e48c4981c673197 https://doi.org/10.5152/tjg.2026.25297

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Prophylactic heparin and mortality in patients with acute respiratory failure in the ICUCohort Study · 2026
2Impact of early heparin therapy on mortality in critically ill patients with sepsis-related acute respiratory distress syndrome: a MIMIC-IV database analysis2025
3Early prophylactic heparin use is associated with reduced mortality in patients with non-traumatic subarachnoid hemorrhagecohort · 2026 · 1 citations
4Reduction of Mortality in General Medical In-patients by Low-Dose Heparin ProphylaxisRCT · 1982 · 187 citations
5Exploring the therapeutic role of early heparin administration in ARDS management: a MIMIC-IV database analysis2024 · 13 citations

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